L2HGDH antibody

Catalog No. ABIN6293250

This anti-L2HGDH antibody is a Rabbit Polyclonal antibody detecting L2HGDH in WB and IF. Suitable for Human and Mouse.

Quick Overview for L2HGDH antibody (ABIN6293250)

Target: L2HGDH (L-2-Hydroxyglutarate Dehydrogenase (L2HGDH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L2HGDH antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-L2HGDH Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human L2HGDH

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IF 1:50 - 1:200

Comment:

Widely expressed, Highly expressed in brain, testis and muscle, Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for L2HGDH

Target: L2HGDH (L-2-Hydroxyglutarate Dehydrogenase (L2HGDH))

Alternative Name: L2HGDH

Background: This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

Molecular Weight: 50.316 kDa

Gene ID: 79944

UniProt: Q9H9P8