PPP1R3B antibody

Catalog No. ABIN6293886

This anti-PPP1R3B antibody is a Rabbit Polyclonal antibody detecting PPP1R3B in WB. Suitable for Mouse and Rat.

Quick Overview for PPP1R3B antibody (ABIN6293886)

Target: PPP1R3B (Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP1R3B Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PPP1R3B

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highly expressed in the liver and, at lower levels, in skeletal muscle, including in vastus lateralis, gastrocnemius and soleus (at protein level), Highest mRNA levels are observed in skeletal muscle, and only moderate levels in liver and heart, Weak expression in placenta and lung

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for PPP1R3B

Target: PPP1R3B (Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B))

Alternative Name: PPP1R3B

Background: This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.

Molecular Weight: 32.695 kDa

Gene ID: 79660

UniProt: Q86XI6

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process