FTL antibody (AA 38-165)

Catalog No. ABIN6294503

The Mouse Monoclonal anti-FTL antibody has been validated for WB, IHC, IF and FACS. It is suitable to detect FTL in samples from Human.

Quick Overview for FTL antibody (AA 38-165) (ABIN6294503)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-FTL Antibody

Binding Specificity: AA 38-165

Purpose: Mouse anti-Human Ferritin Antibody (light chain specific) [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin antibody (light chain specific).

Immunogen: Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin antibody (light chain specific).

Application Details

Application Notes: Western blot: 1-2 μg/mL
FACS: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: Ferritin light chain

Background:

Target Description: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Gene Symbol: FTL

Gene ID: 2512

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis