SUMO2 antibody (C-Term)

Catalog No. ABIN6294661

This Mouse Monoclonal antibody specifically detects SUMO2 in . It exhibits reactivity toward Human and Rat.

Quick Overview for SUMO2 antibody (C-Term) (ABIN6294661)

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SUMO2 antibody is un-conjugated

Application: Please inquire

Product Details anti-SUMO2 Antibody

Binding Specificity: C-Term

Purpose: Mouse Anti-SUMO2 (C-term) Antibody

Immunogen: Purified His-tagged SUMO2 protein was used to produced this monoclonal antibody.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for SUMO2

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Alternative Name: SUMO2

Background:

Target Description: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

Gene Symbol: SUMO2

Gene ID: 6613

UniProt: P61956

Pathways: Methionine Biosynthetic Process