LDL antibody (Center)

Catalog No. ABIN6295353

This anti-LDL antibody is a Rabbit Polyclonal antibody detecting LDL in . Suitable for Human and Mouse.

Quick Overview for LDL antibody (Center) (ABIN6295353)

Target: LDL (Low Density Lipoprotein (LDL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDL antibody is un-conjugated

Application: Please inquire

Product Details anti-LDL Antibody

Binding Specificity: AA 391-419, Center

Purpose: Rabbit Anti-LDLR (Center) Antibody

Immunogen: This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human LDLR.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for LDL

Target: LDL (Low Density Lipoprotein (LDL))

Alternative Name: LDL

Background:

Target Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.

Gene Symbol: LDLR

Gene ID: 3949

UniProt: P01130