FOXP3 antibody (N-Term)

Catalog No. ABIN6295492

This Mouse Monoclonal antibody specifically detects FOXP3 in IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for FOXP3 antibody (N-Term) (ABIN6295492)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXP3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-FOXP3 Antibody

Binding Specificity: N-Term

Purpose: Mouse anti-Human/Mouse FOXP3 Antibody [IHC only]

Specificity: Predominantly nuclear, some cytoplasmic

Purification: An N-terminal recombinant protein fragment was used as the immunogen for this FOXP3 antibody.

Immunogen: An N-terminal recombinant protein fragment was used as the immunogen for this FOXP3 antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: Forkhead box protein P3

Background:

Target Description: The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. FOXP3 is essential for normal immune homeostasis. It represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Gene Symbol: FOXP3///IPEX///JM2

Gene ID: 50943

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation