CD6 antibody

Catalog No. ABIN6295928

The Mouse Monoclonal anti-CD6 antibody has been validated for FACS, WB and IF. It is suitable to detect CD6 in samples from Human and Mouse.

Quick Overview for CD6 antibody (ABIN6295928)

Target: CD6

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CD6 Antibody

Purpose: Mouse anti-Human/Mouse CD6 Antibody [Sodium Azide Free]

Specificity: Cell surface and cytoplasmic

Purification: A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.

Immunogen: A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.

Application Details

Application Notes: Western blot: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD6

Target: CD6

Alternative Name: T-cell differentiation antigen CD6

Background:

Target Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular "scavenger receptor cysteine-rich" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Gene Symbol: CD6

Gene ID: 923

UniProt: P30203