AMPD3 antibody

Catalog No. ABIN6296990

The Mouse Monoclonal anti-AMPD3 antibody has been validated for IF, IHC, ICC and FACS. It is suitable to detect AMPD3 in samples from Human.

Quick Overview for AMPD3 antibody (ABIN6296990)

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AMPD3 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-AMPD3 Antibody

Purpose: Mouse anti-Human AMPD3 Antibody [Sodium Azide Free]

Specificity: Cytoplasmic, membrane

Purification: Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.

Immunogen: Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.

Application Details

Application Notes: Flow Cytometry: 1-2 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL,Immunocytochemistry: 1-2 μg/mL for 30 min at RT
Immunohistology (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for AMPD3

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Alternative Name: AMP deaminase 3

Background:

Target Description: It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This mAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This mAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Gene Symbol: AMPD3

Gene ID: 272

UniProt: Q01432