Cadherin-16 antibody

Catalog No. ABIN6297278

The Mouse Monoclonal anti-Cadherin-16 antibody has been validated for IHC, IF and FACS. It is suitable to detect Cadherin-16 in samples from Human, Mouse, Rat, Dog and Rabbit.

Quick Overview for Cadherin-16 antibody (ABIN6297278)

Target: Cadherin-16 (CDH16)

Reactivity: Human, Mouse, Rat, Dog, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-Cadherin-16 Antibody

Purpose: Mouse anti-Human/Mouse/Rat/Rabbit/Dog Cadherin 16 Antibody [Sodium Azide Free]

Specificity: Cell surface with some cytoplasmic

Purification: Recombinant human protein was used as the immunogen for the anti-Cadherin 16 antibody.

Immunogen: Recombinant human protein was used as the immunogen for the anti-Cadherin 16 antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: Cadherin-16

Background:

Target Description: This mAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Gene Symbol: CDH16///UNQ695///PRO1340

Gene ID: 1014

UniProt: O75309