MUC6 antibody

Catalog No. ABIN6297409

This Mouse Monoclonal antibody specifically detects MUC6 in IHC, IF, WB and FACS. It exhibits reactivity toward Human.

Quick Overview for MUC6 antibody (ABIN6297409)

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC6 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-MUC6 Antibody

Purpose: Mouse anti-Human Mucin-6 Antibody [Sodium Azide Free]

Specificity: Cytoplasmic & secreted

Purification: Recombinant human protein was used as the immunogen for the Mucin-6 antibody.

Immunogen: Recombinant human protein was used as the immunogen for the Mucin-6 antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for MUC6

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Alternative Name: Mucin-6

Background:

Target Description: MUC6 or gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Gene Symbol: MUC6

Gene ID: 4588

UniProt: Q6W4X9