CD27 antibody (CD27 Molecule)

Details for Product anti-CD27 Antibody No. ABIN6297638
Antigen
  • TNFRSF7
  • S152
  • Tnfrsf7
  • Tp55
  • S152. LPFS2
  • T14
  • CD27 molecule
  • CD27 antigen
  • CD27
  • Cd27
Reactivity
Human
330
87
51
11
7
7
7
6
2
2
2
1
1
1
Host
Mouse
193
131
37
5
3
1
Clonality
Monoclonal
Conjugate
This CD27 antibody is un-conjugated
39
37
25
22
8
6
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF)
264
78
76
70
61
37
26
16
15
10
6
6
5
3
2
2
2
2
2
1
Options
Purpose Mouse anti-Human CD27 Antibody [Sodium Azide Free]
Immunogen Sezary cells were used as the immunogen for the CD27 antibody.
Specificity Cell surface
Purification Sezary cells were used as the immunogen for the CD27 antibody.
Plasmids, Primers & others Plasmids, Primers & others CD27 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD27 antigen (CD27 Antibody Abstract)
Background

Target Description: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Gene Symbol: CD27///TNFRSF7

Gene ID 939
UniProt P26842
Pathways Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.