CD27 antibody (CD27 Molecule)

Details for Product anti-CD27 Antibody No. ABIN6297638
Target
Reactivity
Human
216
70
43
11
7
7
7
6
2
2
2
1
1
1
Host
Mouse
115
97
27
5
3
1
Clonality
Monoclonal
Conjugate
This CD27 antibody is un-conjugated
24
22
20
16
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF)
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55
53
47
41
24
19
16
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8
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6
3
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2
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Options
Purpose Mouse anti-Human CD27 Antibody [Sodium Azide Free]
Immunogen Sezary cells were used as the immunogen for the CD27 antibody.
Specificity Cell surface
Purification Sezary cells were used as the immunogen for the CD27 antibody.
Target
Alternative Name CD27 antigen (CD27 Antibody Abstract)
Background

Target Description: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Gene Symbol: CD27///TNFRSF7

Gene ID 939
UniProt P26842
Pathways Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.