CD6 antibody

Catalog No. ABIN6297742

This Mouse Monoclonal antibody specifically detects CD6 in FACS, IF and IHC. It exhibits reactivity toward Human.

Quick Overview for CD6 antibody (ABIN6297742)

Target: CD6

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-CD6 Antibody

Purpose: Mouse anti-Human CD6 Antibody [Sodium Azide Free]

Specificity: Cell surface and cytoplasmic

Purification: The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody.

Immunogen: The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody.

Application Details

Application Notes: FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD6

Target: CD6

Alternative Name: T-cell differentiation antigen CD6

Background:

Target Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular ""scavenger receptor cysteine-rich "" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. It shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. CD6 antibody can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Gene Symbol: CD6

Gene ID: 923

UniProt: P30203