CD70 antibody

Catalog No. ABIN6297746

The Mouse Monoclonal anti-CD70 antibody has been validated for ELISA, FACS, IP, IF, IHC (fro), ProA and Func. It is suitable to detect CD70 in samples from Human.

Quick Overview for CD70 antibody (ABIN6297746)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD70 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Proliferation Assay (ProA), Functional Studies (Func)

Product Details anti-CD70 Antibody

Purpose: Mouse anti-Human CD70 Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.

Immunogen: The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.

Application Details

Application Notes: ELISA (order Ab without BSA)
Functional Activity: Inhibits T cell proliferation induced by dendritic cells (Order SAF formulation) (1)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunoprecipitation: 0.5-1 μg/500 μg protein lysate
Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70 antigen

Background:

Target Description: CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Gene Symbol: CD70///CD27L///CD27LG///TNFSF7

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints