For best experience we recommend to activate Javascript in your browser.

CD45 antibody

PTPRC Reactivity: Human FACS, IHC, IF Host: Mouse Monoclonal unconjugated

Catalog No. ABIN6297770

Datasheet as PDF

Target See all CD45 (PTPRC) Antibodies

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
Reactivity
355

222

83

33

20

19

16

14

10

10

7

6

4

3

3

3

2

1

1

1

1

1
Human
Host
295

167

126

2

1

1
Mouse
Compatible Secondaries
Clonality
470

115

1
Monoclonal
Conjugate
180

58

53

44

40

14

11

11

11

10

10

8

6

5

5

5

5

5

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1
This CD45 antibody is un-conjugated
Application
499

184

180

120

119

56

50

48

42

27

15

13

13

13

12

9

5

3

2

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose

Mouse anti-Human CD45RB Antibody [Sodium Azide Free]

Specificity

Cell surface and cytoplasmic

Purification

The non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V) was used as the immunogen for this antibody.

Immunogen

The non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V) was used as the immunogen for this antibody.

Top Product

Discover our top product PTPRC Primary Antibody
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC Reactivity: Human, Dog FACS, IHC, WB, StM Host: Mouse Monoclonal 2B11-PD7-26 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC Reactivity: Human FACS, WB, IP, IHC (p), ICC Host: Mouse Monoclonal MEM-28 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 193-575) antibody
PTPRC Reactivity: Human IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 371-556) antibody
PTPRC Reactivity: Mouse IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-575) antibody
PTPRC Reactivity: Human FACS, IHC, WB, IF, ELISA Host: Mouse Monoclonal 17H9D4 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (C-Term) antibody
PTPRC Reactivity: Human, Mouse, Rat, Dog, Chicken, Cow, Cat, Sheep, Rabbit, Guinea Pig, Pig, Goat, Horse, Monkey, Avian, Donkey, Hamster WB, IHC (p), IHC (f) Host: Goat Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibody
PTPRC Reactivity: Human FACS, IHC, ELISA Host: Mouse Monoclonal 1B9B10 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 928-989) antibody
PTPRC Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 5D3A3 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibody
PTPRC Reactivity: Human FACS, IHC, WB, ELISA, ICC Host: Mouse Monoclonal 2H3E2 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC Reactivity: Human FACS, IHC, WB, IF, StM Host: Rabbit Monoclonal PTPRC-2877R unconjugated Recombinant Antibody

Application Notes

FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1.0 μg/mL for 30 minutes at RT (1)

Restrictions

For Research Use only
Buffer

In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative

Azide free

Storage

4 °C,-20 °C

Storage Comment

2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Target

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

Alternative Name

Receptor-type tyrosine-protein phosphatase C (PTPRC Products)

Background

Target Description: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. antibody to CD45R is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Gene Symbol: PTPRC///CD45

Gene ID

5788

UniProt

P08575

Pathways

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling