BCL2 antibody (B-Cell CLL/lymphoma 2) (Biotin)

Details for Product anti-BCL2 Antibody No. ABIN6297831
Antigen
  • Bcl-2
  • PPP1R50
  • bcl-2
  • AW986256
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • BCL-2
  • Bcl2
  • BCL2, apoptosis regulator
  • B cell leukemia/lymphoma 2
  • B-cell CLL/lymphoma 2a
  • B-cell CLL/lymphoma 2 protein
  • BCL2
  • Bcl2
  • bcl2a
  • BCL-2
Reactivity
Human
1030
250
232
52
39
18
11
6
3
3
3
2
1
1
Host
Rabbit
675
432
9
6
2
Clonality
Polyclonal
Conjugate
This BCL2 antibody is conjugated to Biotin
55
46
36
33
29
22
14
14
14
14
14
14
10
7
7
7
7
7
7
7
7
7
7
7
7
7
6
6
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
832
405
335
326
308
186
166
155
79
55
40
31
30
26
17
15
15
9
3
2
2
1
1
1
1
1
Options
Purpose Rabbit anti-Human BCL2 Biotinylated Antibody
Immunogen This antibody was produced from antiserum of rabbits immunized with a recombinant protein immunogen. The IgG fraction was purified by Protein G/A affinity chromatography.
Plasmids, Primers & others Plasmids, Primers & others BCL2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name BCL2 (BCL2 Antibody Abstract)
Background

Target Description: Bcl-2  (B-cell lymphoma 2), encoded in humans by the  BCL2  gene, is the founding member of the  Bcl-2 family  of  regulator proteins  that regulate cell death (apoptosis), by either inducing (pro-apoptotic) it or inhibiting it (anti-apoptotic). Bcl-2 is specifically considered as an important anti-apoptotic protein and is thus classified as an oncogene.
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Application Notes ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)
Restrictions For Research Use only
Reconstitution A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.
Storage 4 °C,-20 °C,-80 °C
Storage Comment -20°C
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