ARHGEF1 antibody (rho Guanine Nucleotide Exchange Factor (GEF) 1)

Details for Product anti-ARHGEF1 Antibody No. ABIN6298119
Antigen
  • arhgef1
  • cb473
  • zgc:158261
  • ARHGEF1
  • GEF1
  • LBCL2
  • LSC
  • P115-RHOGEF
  • SUB1.5
  • Lbcl2
  • Lsc
  • Rho guanine nucleotide exchange factor (GEF) 1a
  • Rho guanine nucleotide exchange factor 1
  • Rho guanine nucleotide exchange factor (GEF) 1
  • arhgef1a
  • ARHGEF1
  • arhgef1
  • Arhgef1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
68
24
22
1
1
1
1
Host
Rabbit
62
6
Clonality
Polyclonal
Conjugate
This ARHGEF1 antibody is un-conjugated
3
2
2
2
2
2
1
1
1
1
1
1
Application
58
37
10
7
4
3
2
1
1
Options
Purpose Rabbit Anti-ARHGEF1 Antibody,
Plasmids, Primers & others Plasmids, Primers & others ARHGEF1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name ARHGEF1 (ARHGEF1 Antibody Abstract)
Background

Target Description: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2- induced RhoA activation.

Gene Symbol: ARHGEF1
Gene ID 9138
UniProt Q92888
Pathways Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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