ARHGEF1 antibody (AA 783-912)

Catalog No. ABIN1678742

The Rabbit Polyclonal anti-ARHGEF1 antibody is suitable to detect ARHGEF1 in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for ARHGEF1 antibody (AA 783-912) (ABIN1678742)

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ARHGEF1 Antibody

Binding Specificity: AA 783-912

Sequence: PLLSSSENGN GGRETSPADA RTERILSDLL PFCRPGPEGQ LAATALRKVL SLKQLLFPAE EDNGAGPPRD GDGVPGGGPL SPARTQEIQE NLLSLEETMK QLEELEEEFC RLRPLLSQLG GNSVPQPGCT

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 783-912 of human ARHGEF1 (NP_004697.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGEF1

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Alternative Name: ARHGEF1

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.,ARHGEF1,GEF1,LBCL2,LSC,P115-RHOGEF,SUB1.5,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Microtubules,ARHGEF1

Molecular Weight: 98 kDa/102 kDa/104 kDa/105 kDa

Gene ID: 9138

UniProt: Q92888

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling