ARHGEF1 antibody (AA 830-927)

Catalog No. ABIN522597

Cited in 1 publication. The Mouse Monoclonal anti-ARHGEF1 antibody (Clone 4C4) (ABIN522597) specifically detects ARHGEF1 in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for ARHGEF1 antibody (AA 830-927) (ABIN522597)

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ARHGEF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 4C4

Product Details anti-ARHGEF1 Antibody

Binding Specificity: AA 830-927

Purpose: Mouse monoclonal antibody raised against a partial recombinant ARHGEF1.

Sequence: CRPGPEGQLA ATALRKVLSL KQLLFPAEED NGAGPPRDGD GVPGGGPLSP ARTQEIQENL LSLEETMKQL EELEEEFCRL RPLLSQLGGN SVPQPGCT

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ARHGEF1 (AAH34013.2, 830 a.a. ~ 927 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ARHGEF1 antibody (ABIN522597)

Zizer, Beilke, Bäuerle, Schilling, Möhnle, Adler, Fischer, Wagner: "Loss of Lsc/p115 protein leads to neuronal hypoplasia in the esophagus and an achalasia-like phenotype in mice." in: Gastroenterology, Vol. 139, Issue 4, pp. 1344-54, (2010) (PubMed).

Target Details for ARHGEF1

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Alternative Name: ARHGEF1

Background: Full Gene Name: Rho guanine nucleotide exchange factor (GEF) 1
Synonyms: GEF1,LBCL2,LSC,P115-RHOGEF,SUB1.5

Gene ID: 9138

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling