RUNX1 antibody (Runt-Related Transcription Factor 1)

Details for Product anti-RUNX1 Antibody No. ABIN6298208
Antigen
  • RUNX1
  • runx1
  • AI462102
  • AML1
  • Cbfa2
  • Pebp2a2
  • Pebpa2b
  • AML1-EVI-1
  • AMLCR1
  • CBFA2
  • EVI-1
  • PEBP2aB
  • runxa
  • Runx-1
  • XAML
  • Xaml1
  • aml
  • aml-1
  • aml1
  • aml1-evi-1
  • amlcr1
  • cbfa2
  • evi-1
  • pebp2ab
  • Aml1
  • uncharacterized LOC473981
  • runt-related transcription factor
  • runt related transcription factor 1
  • runt-related transcription factor 1
  • runt related transcription factor 1 L homeolog
  • LOC473981
  • runt
  • Runx1
  • RUNX1
  • runx1
  • runx1.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
271
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1
Clonality
Polyclonal
Conjugate
This RUNX1 antibody is un-conjugated
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5
4
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Application
256
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Options
Purpose Rabbit Anti-AML1 (Ab-435) Antibody,
Plasmids, Primers & others Plasmids, Primers & others RUNX1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name AML1 (RUNX1 Antibody Abstract)
Background

Target Description: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B- dependent transcriptional activation.

Gene Symbol: RUNX1
Gene ID 861
UniProt Q01196
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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