PODXL antibody (N-Term)

Catalog No. ABIN630292

This Rabbit Polyclonal antibody specifically detects PODXL in WB. It exhibits reactivity toward Human.

Quick Overview for PODXL antibody (N-Term) (ABIN630292)

Target: PODXL (Podocalyxin-Like (PODXL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PODXL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PODXL Antibody

Binding Specificity: N-Term

Specificity: PODXL antibody was raised against the N terminal of PODXL

Purification: Purified

Immunogen: PODXL antibody was raised using the N terminal of PODXL corresponding to a region with amino acids TTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSHSVTTDLTSTKAEHLTT

Application Details

Application Notes: WB: 5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PODXL Blocking Peptide, (ABIN5615448), is also available for use as a blocking control in assays to test for specificity of this PODXL antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PODXL antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Alternative Name: PODXL

Background: PODXL is a member of the sialomucin protein family. PODXL was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of PODXL include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Molecular Weight: 53 kDa (MW of target protein)

Pathways: Tube Formation