Keratin 2 antibody (Middle Region)

Catalog No. ABIN631441

This Rabbit Polyclonal antibody specifically detects Keratin 2 in WB and IHC. It exhibits reactivity toward Human and Dog.

Quick Overview for Keratin 2 antibody (Middle Region) (ABIN631441)

Target: Keratin 2 (KRT2)

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Keratin 2 Antibody

Binding Specificity: Middle Region

Specificity: KRT2 A antibody was raised against the middle region of Krt2

Purification: Affinity purified

Immunogen: KRT2 A antibody was raised using the middle region of Krt2 corresponding to a region with amino acids EVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELN

Application Details

Application Notes: WB: 0.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

KRT2A Blocking Peptide, (ABIN938179), is also available for use as a blocking control in assays to test for specificity of this KRT2A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KRT0 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for Keratin 2

Target: Keratin 2 (KRT2)

Alternative Name: KRT2A

Background: KRT2A is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma.

Molecular Weight: 70 kDa (MW of target protein)