Acylglycerol Kinase antibody (N-Term)
Quick Overview for Acylglycerol Kinase antibody (N-Term) (ABIN632105)
Target
See all Acylglycerol Kinase (AGK) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- AGK antibody was raised against the N terminal of AGK
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Purification
- Affinity purified
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Immunogen
- AGK antibody was raised using the N terminal of AGK corresponding to a region with amino acids KKLLELMENTDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLGE
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Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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AGK Blocking Peptide, (ABIN939868), is also available for use as a blocking control in assays to test for specificity of this AGK antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of AGK antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Acylglycerol Kinase (AGK)
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Alternative Name
- AGK
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Background
- AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
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Molecular Weight
- 47 kDa (MW of target protein)
Target
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