ORAI1 antibody (N-Term)

Catalog No. ABIN635032

This Rabbit Polyclonal antibody specifically detects ORAI1 in WB. It exhibits reactivity toward Human.

Quick Overview for ORAI1 antibody (N-Term) (ABIN635032)

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORAI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ORAI1 Antibody

Binding Specificity: N-Term

Specificity: ORAI1 antibody was raised against the N terminal of ORAI1

Purification: Affinity purified

Immunogen: ORAI1 antibody was raised using the N terminal of ORAI1 corresponding to a region with amino acids HPEPAPPPSRSSPELPPSGGSTTSGSRRSRRRSGDGEPPGAPPPPPSAVT

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

ORAI1 Blocking Peptide, (ABIN939195), is also available for use as a blocking control in assays to test for specificity of this ORAI1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ORAI1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for ORAI1

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Alternative Name: ORAI1

Background: ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction.

Molecular Weight: 33 kDa (MW of target protein)

Pathways: TCR Signaling, BCR Signaling