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Follistatin antibody

This anti-Follistatin antibody is a Rabbit Polyclonal antibody detecting Follistatin in WB, ELISA and Inhibition. Suitable for Human.
Catalog No. ABIN636639

Quick Overview for Follistatin antibody (ABIN636639)

Target

See all Follistatin (FST) Antibodies
Follistatin (FST)

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Follistatin antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
  • Purification

    Purified

    Immunogen

    Follistatin antibody was raised in rabbit using highly pure recombinant human Follistatin as the immunogen.
  • Application Notes

    ELISA: 0.5-2 µg/mL, Inhibition: 8-12 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Concentration

    Lot specific

    Buffer

    Lyophilized from PBS, pH 7.2.

    Handling Advice

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • Target

    Follistatin (FST)

    Alternative Name

    Follistatin

    Background

    Follistatin is a secreted protein that binds to ligands of the TGF beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues.

    Molecular Weight

    31.5 kDa (predicted detection band MW)

    Pathways

    Negative Regulation of Hormone Secretion
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