BACE1 antibody

Catalog No. ABIN636992

The Rabbit Polyclonal anti-BACE1 antibody has been validated for IHC (p). It is suitable to detect BACE1 in samples from Human.

Quick Overview for BACE1 antibody (ABIN636992)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BACE1 Antibody

Purification: Affinity chromatography purified

Immunogen: BACE1 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Application Details

Application Notes: IHC-P: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE1

Background: Beta-site APP cleaving enzyme 1 (BACE1) is an enzyme that in humans is encoded by the BACE1 gene. Beta-Secretase is an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein contains two active site aspartate residues in its extracellular protein domain and may function as a dimer.