COLEC12 antibody

Catalog No. ABIN6389791

The Rabbit Polyclonal anti-COLEC12 antibody has been validated for WB and ELISA. It is suitable to detect COLEC12 in samples from Human, Mouse and Rat.

Quick Overview for COLEC12 antibody (ABIN6389791)

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COLEC12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-COLEC12 Antibody

Purpose: Unconjugated Rabbit polyclonal to COL12

Specificity: COL12 Polyclonal Antibody detects endogenous levels of protein.

Purification: COL12 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Comment:

Expressed in perivascular macrophages. Expressed in plaques-surrounding reactive astrocytes and in perivascular astrocytes associated with cerebral amyloid angiopathy (CAA) in the temporal cortex of Alzheimer patient (at protein level). Strongly expressed in placenta. Moderately expressed in heart, skeletal muscle, small intestine and lung. Weakly expressed in brain, colon, thymus and kidney. Expressed in nurse-like cells. Expressed in reactive astrocytes and vascular/perivascular cells in the brain of Alzheimer patient.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for COLEC12

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Alternative Name: COL12

Molecular Weight: 81 kDa

Gene ID: 81035

UniProt: Q5KU26

Pathways: Activation of Innate immune Response