C1q antibody
C1q
Reactivity: Human
ELISA, FACS, IHC (fro), IF
Host: Mouse
Monoclonal
unconjugated
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- Target See all C1q Antibodies
- C1q (Complement Fragment C1q (C1q))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This C1q antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
- Purpose
- Mouse Anti-Human C1q
- Specificity
- DS-MB-02778 recognizes human complement component 1, q subcomponent (C1q), a 156kDa secreted protein. C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.
- Characteristics
- Blood Coagulation Proteins
- Purification
- Purified
- Immunogen
- Binds globular head domain of C1q, purified from human plasma.
- Isotype
- IgG1
- Top Product
- Discover our top product C1q Primary Antibody
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- Application Notes
- Immunohistology - Frozen, ELISA (dilution: 1:500, 1:1000), Flow Cytometry, Immunofluorescence
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Borate buffered saline, pH 8.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- C1q (Complement Fragment C1q (C1q))
- Alternative Name
- C1q (C1q Products)
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