HCV E2 antibody (AA 384-665)

Catalog No. ABIN640224

This anti-HCV E2 antibody is a Goat antibody detecting HCV E2 in WB and ELISA. Suitable for Hepatitis C Virus (HCV).

Quick Overview for HCV E2 antibody (AA 384-665) (ABIN640224)

Target: HCV E2 (Hepatitis C Virus Envelope Protein E2 (HCV E2))

Reactivity: Hepatitis C Virus (HCV)

Host: Goat

Conjugate: This HCV E2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HCV E2 Antibody

Binding Specificity: AA 384-665

Specificity: E2 envelope protein

Characteristics: Goat Anti-Hepatitic C Virus (HCV) E2 (aa 384-665)

Purification: Purified

Immunogen: Recombinant E2 (genotype 1a)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 4-5 mg/ml (OD280nm, E^0.1% = 1.4)

Buffer: 0.01M PBS, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for HCV E2

Target: HCV E2 (Hepatitis C Virus Envelope Protein E2 (HCV E2))

Target Type: Viral Protein

Background: Uev1A, also designated Uev1, UBE2V1 (for ubiquitin-conjugating enzyme E2 variant 1) and CROC1, shows sequence similarity to other ubiquitin-conjugating enzymes, but lacks the conserved cysteine residue critical for their catalytic activity. Therefore, Uev1A does not have ubiquitin-conjugating activity in vitro. However, constitutive expression of exogenous Uev1A in colon carcinoma cells inhibits their capacity to differentiate upon confluence. Studies on recombinant Uev1A show that it localizes to the nucleus, excluding the nucleolar regions. Uev1A functions with TRAF6, a RING domain protein, to catalyze the synthesis of unique polyubiquitin chains linked through Lysine 63 of ubiquitin. The gene encoding Uev1A maps to human chromosome 20q13.2.