CD63 antibody (C-Term)

Catalog No. ABIN651526

This Rabbit Polyclonal antibody specifically detects CD63 in FACS, WB and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CD63 antibody (C-Term) (ABIN651526)

Target: CD63

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD63 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB26813

Product Details anti-CD63 Antibody

Binding Specificity: AA 163-190, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CD63.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. WB: 1:2000. WB: 1:2000. WB: 1:1000. WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Expiry Date: 6 months

References for anti-CD63 antibody (ABIN651526)

Meng, Müller, Milde-Langosch, Trillsch, Pantel, Schwarzenbach: "Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer." in: Oncotarget, Vol. 7, Issue 13, pp. 16923-35, (2017) (PubMed).

García-Contreras, Vera-Donoso, Hernández-Andreu, García-Verdugo, Oltra: "Therapeutic potential of human adipose-derived stem cells (ADSCs) from cancer patients: a pilot study." in: PLoS ONE, Vol. 9, Issue 11, pp. e113288, (2016) (PubMed).

Target Details for CD63

Target: CD63

Alternative Name: CD63

Background: CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.

Molecular Weight: 25637

Gene ID: 967

NCBI Accession: NP_001244318, NP_001244319, NP_001244320, NP_001244321, NP_001244329, NP_001244330, NP_001254627, NP_001771

UniProt: P08962