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IGF1R antibody (N-Term)
IGF1R
Reactivity: Human
WB, FACS, IF, IHC (p)
Host: Rabbit
Polyclonal
RB15292
unconjugated
Product Details anti-IGF1R Antibody
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Target
See all IGF1R Antibodies
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Binding Specificity
All epitopes for IGF1R antibodies
AA 51-77, N-Term
Reactivity
All reactivities for IGF1R antibodies
Human
Host
All hosts for IGF1R antibodies
Rabbit
Clonality
All clonalities for IGF1R antibodies
Polyclonal
Conjugate
All conjugates for IGF1R antibodies
This IGF1R antibody is un-conjugated
Application
All applications for IGF1R antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
M, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This IGF1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human IGF1R.
Clone
RB15292
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for IGF1R
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Target
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Alternative Name
IGF1R (IGF1R Products )
Background
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Molecular Weight
154793
Gene ID
3480
NCBI Accession
NP_000866
UniProt
P08069
Pathways
RTK Signaling , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Autophagy
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