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IGF1R antibody (N-Term)

IGF1R Reactivity: Human WB, FACS, IF, IHC (p) Host: Rabbit Polyclonal RB15292 unconjugated
Catalog No. ABIN652374
  • Target See all IGF1R Antibodies
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    Binding Specificity
    • 23
    • 23
    • 19
    • 14
    • 12
    • 12
    • 12
    • 10
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-77, N-Term
    Reactivity
    • 187
    • 110
    • 93
    • 16
    • 8
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 172
    • 29
    • 2
    • 1
    Rabbit
    Clonality
    • 174
    • 30
    Polyclonal
    Conjugate
    • 125
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This IGF1R antibody is un-conjugated
    Application
    • 131
    • 72
    • 60
    • 59
    • 32
    • 24
    • 18
    • 13
    • 13
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This IGF1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human IGF1R.
    Clone
    RB15292
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IGF1R Primary Antibody
  • Application Notes
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    Alternative Name
    IGF1R (IGF1R Products)
    Background
    The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
    Molecular Weight
    154793
    Gene ID
    3480
    NCBI Accession
    NP_000866
    UniProt
    P08069
    Pathways
    RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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