SESN1 antibody (N-Term)

Catalog No. ABIN652375

Product Details anti-SESN1 Antibody

Target: SESN1 (Sestrin 1 (SESN1))

Binding Specificity: AA 14-43, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESN1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human Sestrin-1.

Clone: RB18600

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-SESN1 antibody (ABIN652375)

Ye, Palm, Peng, King, Lindsten, Li, Koumenis, Thompson: "GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2." in: Genes & development, Vol. 29, Issue 22, pp. 2331-6, (2015) (PubMed).

Target Details for SESN1

Target: SESN1 (Sestrin 1 (SESN1))

Alternative Name: Sestrin-1 (SESN1 Products)

Background: Sestrin-1 is involved in the reduction of peroxiredoxins. This protein may also be regulator of cellular growth.

Molecular Weight: 56557

Gene ID: 27244

NCBI Accession: NP_001186862, NP_001186863, NP_055269

UniProt: Q9Y6P5