ADCY8 antibody (AA 946-972)

Catalog No. ABIN2842527

This Rabbit Polyclonal antibody specifically detects ADCY8 in WB, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for ADCY8 antibody (AA 946-972) (ABIN2842527)

Target: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB22741

Product Details anti-ADCY8 Antibody

Binding Specificity: AA 946-972

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ADCY8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-972 amino acids from the Central region of human ADCY8.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ADCY8

Target: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Alternative Name: ADCY8

Background: ADCY8 is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase provided by RefSeq].

Molecular Weight: 140122

Gene ID: 114

NCBI Accession: NP_001106

UniProt: P40145

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma