PYCR1 antibody (C-Term)

Catalog No. ABIN653849

The Rabbit Polyclonal anti-PYCR1 antibody has been validated for WB, FACS and IHC (p). It is suitable to detect PYCR1 in samples from Human. There is 1 publication available.

Quick Overview for PYCR1 antibody (C-Term) (ABIN653849)

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYCR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB24671

Product Details anti-PYCR1 Antibody

Binding Specificity: AA 291-319, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PYCR1 antibody (ABIN653849)

Zeng, Zhu, Liao, Zhuo, Yang, Wu, Wang: "Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 2, pp. 27, (2017) (PubMed).

Target Details for PYCR1

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Alternative Name: PYCR1

Background: This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.

Molecular Weight: 33361

Gene ID: 5831

NCBI Accession: NP_001269209, NP_001269210, NP_008838, NP_722546

UniProt: P32322