IGF2BP1 antibody (C-Term)

Catalog No. ABIN654423

This anti-IGF2BP1 antibody is a Rabbit Polyclonal antibody detecting IGF2BP1 in WB, FACS and IHC (p). Suitable for Human and Mouse. This Primary Antibody has been cited in 2+ publications.

Quick Overview for IGF2BP1 antibody (C-Term) (ABIN654423)

Target: IGF2BP1 (Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2BP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21526

Product Details anti-IGF2BP1 Antibody

Binding Specificity: AA 508-534, C-Term

Predicted Reactivity: X, Rat, C, Zf

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IGF2BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-534 amino acids from the C-terminal region of human IGF2BP1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-IGF2BP1 antibody (ABIN654423)

Hashimoto, Yamamoto, Ogasawara, Sato, Yamamoto, Katoh, Kubota, Shiraishi, Kojima, Himi, Tsutsumi, Yokota: "Mumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production." in: PLoS ONE, Vol. 11, Issue 8, pp. e0161793, (2017) (PubMed).

Yang, Xu, Lu, Li, Sun, Guo, Xue, Guan: "Quantitative Analysis of Differential Proteome Expression in Bladder Cancer vs. Normal Bladder Cells Using SILAC Method." in: PLoS ONE, Vol. 10, Issue 7, pp. e0134727, (2015) (PubMed).

Target Details for IGF2BP1

Target: IGF2BP1 (Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1))

Alternative Name: IGF2BP1

Background: IGF2BP1 is a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 63481

Gene ID: 10642

NCBI Accession: NP_001153895, NP_006537

UniProt: Q9NZI8