alpha-Mannosidase II antibody (AA 456-482)

Catalog No. ABIN654920

Product Details anti-alpha-Mannosidase II Antibody

Target: alpha-Mannosidase II (MAN2A1) (Mannosidase, Alpha, Class 2A, Member 1 (MAN2A1))

Binding Specificity: AA 456-482

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha-Mannosidase II antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAN2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-482 amino acids from the Central region of human MAN2A1.

Clone: RB22470

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for alpha-Mannosidase II

Target: alpha-Mannosidase II (MAN2A1) (Mannosidase, Alpha, Class 2A, Member 1 (MAN2A1))

Alternative Name: MAN2A1 (MAN2A1 Products)

Background: This gene encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.

Molecular Weight: 131141

Gene ID: 4124

NCBI Accession: NP_002363

UniProt: Q16706