PHOX2B antibody (AA 104-130)

Catalog No. ABIN655288

This Rabbit Polyclonal antibody specifically detects PHOX2B in WB and IF. It exhibits reactivity toward Mouseand has been mentioned in 1 publication.

Quick Overview for PHOX2B antibody (AA 104-130) (ABIN655288)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: RB28842

Product Details anti-PHOX2B Antibody

Binding Specificity: AA 104-130

Predicted Reactivity: H, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PHOX2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-130 amino acids from the Central region of human PHOX2B.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PHOX2B antibody (ABIN655288)

Burbach, Hellemons, Grant, Pant: "The homeodomain transcription factor Phox2 in the stellate ganglion of the squid Loligo pealei." in: Biology open, Vol. 4, Issue 8, pp. 954-960, (2015) (PubMed).

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHOX2B

Background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq].

Molecular Weight: 31621

Gene ID: 8929

NCBI Accession: NP_003915

UniProt: Q99453