WFDC1 antibody (C-Term)

Catalog No. ABIN656404

This Rabbit Polyclonal antibody specifically detects WFDC1 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for WFDC1 antibody (C-Term) (ABIN656404)

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WFDC1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19963

Product Details anti-WFDC1 Antibody

Binding Specificity: AA 148-177, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This WFDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-177 amino acids from the C-terminal region of human WFDC1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:100. IHC-P: 1:100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: WFDC1 Antibody (C-term H163) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for WFDC1

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Alternative Name: WFDC1

Background: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

Molecular Weight: 23977

Gene ID: 58189

NCBI Accession: NP_067020

UniProt: Q9HC57