CYP2S1 antibody (C-Term)

Catalog No. ABIN656566

This Rabbit Polyclonal antibody specifically detects CYP2S1 in WB, IF and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CYP2S1 antibody (C-Term) (ABIN656566)

Target: CYP2S1 (Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2S1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB17020

Product Details anti-CYP2S1 Antibody

Binding Specificity: AA 399-428, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CYP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human CYP2S1.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CYP2S1 antibody (ABIN656566)

Yang, Zhou, Li, Tong, Sun, Qing, Sun, Yang, Hu, Jiang, Yan, He, Wan: "Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines." in: Scientific reports, Vol. 6, pp. 33078, (2016) (PubMed).

Yang, Li, Li, Tong, Hu, Yang, Yan, He, Wan: "CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling." in: Experimental cell research, Vol. 331, Issue 2, pp. 377-86, (2015) (PubMed).

Target Details for CYP2S1

Target: CYP2S1 (Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))

Alternative Name: CYP2S1

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens, however, the specific function of the human protein has not been determined.

Molecular Weight: 55817

Gene ID: 29785

NCBI Accession: NP_085125

UniProt: Q96SQ9