FGF2 antibody (Fibroblast Growth Factor 2 (Basic))

Details for Product anti-FGF2 Antibody No. ABIN6566521
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
313
125
99
22
18
18
4
2
2
2
1
1
1
1
1
Host
Rabbit
250
98
9
5
1
1
Clonality
Polyclonal
Conjugate
This FGF2 antibody is un-conjugated
36
20
14
7
7
7
7
7
7
6
6
5
3
3
3
3
3
2
2
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
232
183
107
55
39
23
22
22
22
17
13
13
11
7
6
5
4
1
1
1
1
1
1
1
1
Options
Immunogen Recombinant protein of human FGF2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name FGF2 (FGF2 Antibody Abstract)
Background

Synonyms: Basic fibroblast growth factor,Basic fibroblast growth factor bFGF,BFGF,FGF 2,FGF B,FGF-2,Fgf2,FGF2 basic,FGF2,FGFB,Fibroblast growth factor 2 (basic),Fibroblast growth factor 2,Fibroblast growth factor,basic,HBGF 2,HBGF-2,HBGF2,HBGH 2,HBGH2,Heparin binding growth factor 2 precursor,Heparin-binding growth factor 2,Prostatropin

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Molecular Weight

Observed_MW: 20kDa,36kDa

Calculated_MW: 17kDa/21kDa/22kDa/30kDa

Gene ID 2247
UniProt P09038
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibody (ABIN6566521) Immunohistochemistry of paraffin-embedded rat lung using FGF2 antibody.
Image no. 2 for anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibody (ABIN6566521) Immunohistochemistry of paraffin-embedded rat brain using FGF2 antibody.
Image no. 3 for anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibody (ABIN6566521) Western blot analysis of extracts of various cell lines, using FGF2 antibody.