Neuregulin 1 antibody (NRG1)

Details for Product anti-NRG1 Antibody No. ABIN6566642
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
194
90
78
3
2
1
1
1
1
1
1
Host
Rabbit
203
15
Clonality
Polyclonal
Conjugate
This Neuregulin 1 antibody is un-conjugated
18
8
8
6
5
5
4
4
4
3
3
3
1
1
1
1
1
Application
Western Blotting (WB)
159
82
77
39
27
22
13
11
11
8
8
5
3
3
2
2
1
Options
Immunogen Recombinant protein of human NRG1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name NRG1 (NRG1 Antibody Abstract)
Background

Synonyms: Acetylcholine receptor-inducing activity,Acetylcholine receptor-inducing activity,CHICK,homolog of,ARIA,Breast cancer cell differentiation factor p45,GGF,GGF2,Glial growth factor,Heregulin,heregulin,alpha (45kD,ERBB2 p185-activator),HGL,HRG,HRG1,HRGA,MST131,NDF,Neu differentiation factor,Neuregulin 1,neuregulin 1 type IV beta 1a,neuregulin 1 type IV beta 3,Neuregulin-1,NRG 1,nrg1,NRG1-IT2,NRG1,OTTHUMP00000225398,OTTHUMP00000225419,OTTHUMP00000225420,OTTHUMP00000225421,OTTHUMP00000225422,OTTHUMP00000225477,OTTHUMP00000225545,OTTHUMP00000230603,OTTHUMP00000230605,pro-neuregulin-1,membrane-bound isoform,Pro-NRG1,ProNRG1,Sensory and motor neuron-derived factor,SMDF

Background: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Molecular Weight

Observed_MW: 70kDa

Calculated_MW: 26kDa/31kDa/45- 50kDa/65-71kDa

Gene ID 3084
UniProt Q02297
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Neuregulin 1 (NRG1) antibody (ABIN6566642) Western blot analysis of extracts of MCF-7 cells, using NRG1 antibody.