Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein (IKBKAP) antibody

Details for Product No. ABIN6566783
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
69
34
20
3
3
3
2
2
1
1
1
1
1
Host
Rabbit
73
4
3
Clonality
Polyclonal
Conjugate
Un-conjugated
6
5
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
62
26
13
11
11
7
5
4
3
2
1
1
Options
Immunogen Recombinant protein of human IKBKAP
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name IKBKAP (IKBKAP Antibody Abstract)
Background

Synonyms: DKFZp781H1425,DYS,Dysautonomia (Riley Day syndrome hereditary sensory autonomic neuropathy type III),Elongator complex protein 1,ELP 1,ELP1,ELP1,FD,FLJ12497,IKAP,IkappaB kinase complex associated protein,IkappaB kinase complex-associated protein,ikbkap,IKI 3,IKI3,IKK complex associated protein,IKK complex-associated protein,Inhibitor of kappa light polypeptide gene enhancer in B cells kinase complex associated protein,OTTHUMP00000063889,p150,TOT 1,TOT1

Background: The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight

Observed_MW: 150kDa

Calculated_MW: 150kDa

Gene ID 8518
UniProt O95163
Application Notes WB 1:1000 - 1:4000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Complex-Associated Protein (IKBKAP) antibody (ABIN6566783) Western blot analysis of extracts of various cell lines, using IKBKAP antibody.