IKAP/p150 antibody (AA 1242-1331)

Catalog No. ABIN563666

There is 1 publication for this product available. The Mouse Monoclonal anti-IKAP/p150 antibody is suitable to detect IKAP/p150 in samples from Human. It has been validated for WB, ELISA and IHC (p).

Quick Overview for IKAP/p150 antibody (AA 1242-1331) (ABIN563666)

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IKAP/p150 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6G9

Product Details anti-IKAP/p150 Antibody

Binding Specificity: AA 1242-1331

Purpose: Mouse monoclonal antibody raised against a partial recombinant IKBKAP.

Sequence: VLFLFEFDEQ GRELQKAFED TLQLMERSLP EIWTLTYQQN SATPVLGPNS TANSIMASYQ QQKTSVPVLD AELFIPPKIN RRTQWKLSLL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: IKBKAP (NP_003631, 1242 a.a. ~ 1331 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-IKAP/p150 antibody (ABIN563666)

Lefler, Cohen, Kantor, Cheishvili, Even, Birger, Turetsky, Gil, Even-Ram, Aizenman, Bashir, Maayan, Razin, Reubinoff, Weil: "Familial Dysautonomia (FD) Human Embryonic Stem Cell Derived PNS Neurons Reveal that Synaptic Vesicular and Neuronal Transport Genes Are Directly or Indirectly Affected by IKBKAP Downregulation." in: PLoS ONE, Vol. 10, Issue 10, pp. e0138807, (2015) (PubMed).

Target Details for IKAP/p150

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Alternative Name: IKBKAP

Background: Full Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
Synonyms: DKFZp781H1425,DYS,ELP1,FD,FLJ12497,IKAP,IKI3,TOT1

Gene ID: 8518

NCBI Accession: NM_003640