LILRB2 antibody (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2)

Details for Product anti-LILRB2 Antibody No. ABIN6566787
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
45
4
3
Host
Rabbit
32
13
Clonality
Polyclonal
Conjugate
This LILRB2 antibody is un-conjugated
4
3
2
2
1
1
1
1
1
1
Application
Western Blotting (WB)
27
14
13
8
1
1
1
Options
Immunogen Recombinant protein of human LILRB2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name CD85d (LILRB2 Antibody Abstract)
Background

Synonyms: CD85 antigen-like family member D,CD85d,CD85d antigen,ILT 4,ILT-4,ILT4,Immunoglobulin like transcript 4,Immunoglobulin-like transcript 4,Leukocyte immunoglobulin like receptor 2,Leukocyte immunoglobulin like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor 2,Leukocyte immunoglobulin-like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor,subfamily B (with TM and ITIM domains),member 2,LILRA6,LILRB2,LIR 2,LIR-2,LIR2,LIRb,LIRB2,MIR 10,MIR-10,MIR10,Monocyte/macrophage immunoglobulin like receptor 10,Monocyte/macrophage immunoglobulin-like receptor 10

Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 65kDa

Calculated_MW: 51kDa/55kDa/64kDa/65kDa

Gene ID 10288
UniProt Q8N423
Pathways Cellular Response to Molecule of Bacterial Origin
Application Notes WB 1:1000 - 1:4000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2) antibody (ABIN6566787) Western blot analysis of extracts of various cell lines, using LILRB2 antibody.