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PDX1 antibody

PDX1 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6566802
  • Target See all PDX1 Antibodies
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    Reactivity
    • 105
    • 45
    • 34
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 118
    • 8
    • 2
    Rabbit
    Clonality
    • 113
    • 15
    Polyclonal
    Conjugate
    • 62
    • 10
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDX1 antibody is un-conjugated
    Application
    • 80
    • 53
    • 27
    • 17
    • 15
    • 14
    • 14
    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human PDX1 (NP_000200.1).
    Isotype
    IgG
    Top Product
    Discover our top product PDX1 Primary Antibody
  • Application Notes
    WB 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
    Alternative Name
    PDX1 (PDX1 Products)
    Background
    The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
    Molecular Weight

    Observed_MW: 39kDa

    Calculated_MW: 30kDa

    Gene ID
    3651
    UniProt
    P52945
    Pathways
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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