KREMEN1 antibody (Kringle Containing Transmembrane Protein 1)

Details for Product anti-KREMEN1 Antibody No. ABIN6566960
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
73
17
13
4
4
3
3
2
2
2
1
1
1
1
Host
Rabbit
68
5
4
Clonality
Polyclonal
Conjugate
This KREMEN1 antibody is un-conjugated
6
6
6
6
6
6
Application
Western Blotting (WB)
59
56
35
15
6
3
2
1
1
Options
Immunogen Recombinant protein of human KREMEN1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name KREMEN1 (KREMEN1 Antibody Abstract)
Background

Synonyms: AV002070,Dickkopf receptor,KREM1,KREMEN,Kremen protein 1,Kremen protein 1 precursor,Kremen1,Kringle coding gene marking the eye and the nose,Kringle containing protein marking the eye and the nose,Kringle containing transmembrane protein 1,Kringle containing transmembrane protein,Kringle domain containing transmembrane protein 1,Kringle domain-containing transmembrane protein 1,Kringle-containing protein marking the eye and the nose,KRM1,RP23 293J16.1

Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Molecular Weight

Observed_MW: 70kDa

Calculated_MW: 50kDa/51kDa/53kDa

Gene ID 83999
UniProt Q96MU8
Pathways WNT Signaling
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) antibody (ABIN6566960) Western blot analysis of extracts of various cell lines, using KREMEN1 antibody.