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KREMEN1 antibody (N-Term)

KREMEN1 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357077
  • Target See all KREMEN1 Antibodies
    KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
    Binding Specificity
    • 15
    • 12
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 42
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 39
    • 3
    • 2
    Rabbit
    Clonality
    • 40
    • 4
    Polyclonal
    Conjugate
    • 20
    • 5
    • 5
    • 5
    • 5
    • 4
    This KREMEN1 antibody is un-conjugated
    Application
    • 37
    • 34
    • 20
    • 13
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Kremen at N-term.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Kremen.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KREMEN1 Primary Antibody
  • Application Notes
    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
    Alternative Name
    Kremen Protein 1 (KREMEN1 Products)
    Synonyms
    KREMEN1 antibody, krm1 antibody, kremen antibody, kremem1 antibody, KREMEN antibody, KRM1 antibody, AV002070 antibody, Kremen antibody, Krm1 antibody, si:ct737139.1 antibody, si:dkeyp-7c9.1 antibody, kringle containing transmembrane protein 1 antibody, kringle containing transmembrane protein 1 S homeolog antibody, KREMEN1 antibody, kremen1 antibody, Kremen1 antibody, kremen1.S antibody
    Background
    Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.Synonyms: Dickkopf receptor, KREMEN, KREMEN1, KRM1, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose
    Molecular Weight
    63,201 Da
    Gene ID
    83999
    NCBI Accession
    NP_001034659
    UniProt
    Q96MU8
    Pathways
    WNT Signaling
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