KREMEN1 antibody (N-Term)

Catalog No. ABIN391859

Product Details anti-KREMEN1 Antibody

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Binding Specificity: AA 53-82, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KREMEN1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Predicted Reactivity: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This KREMEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human KREMEN1.

Clone: RB10586

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for KREMEN1

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Alternative Name: KREMEN1 (KREMEN1 Products)

Synonyms: KREMEN1 antibody, krm1 antibody, kremen antibody, kremem1 antibody, KREMEN antibody, KRM1 antibody, AV002070 antibody, Kremen antibody, Krm1 antibody, si:ct737139.1 antibody, si:dkeyp-7c9.1 antibody, kringle containing transmembrane protein 1 antibody, kringle containing transmembrane protein 1 S homeolog antibody, KREMEN1 antibody, kremen1 antibody, Kremen1 antibody, kremen1.S antibody

Background: KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. This protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.

Molecular Weight: 51744

Gene ID: 83999

NCBI Accession: NP_001034659, NP_114434

UniProt: Q96MU8

Pathways: WNT Signaling