SLC6A5 antibody

Catalog No. ABIN6567212

The Rabbit Polyclonal anti-SLC6A5 antibody has been validated for WB. It is suitable to detect SLC6A5 in samples from Human, Rat and Mouse.

Quick Overview for SLC6A5 antibody (ABIN6567212)

Target: SLC6A5 (Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC6A5 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SLC6A5

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLC6A5

Target: SLC6A5 (Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5))

Alternative Name: SLC6A5

Background:

Synonyms: Glycine transporter,Glycine transporter type 2,GlyT-2,GlyT2,NET1,SC6A5,SC6AC5,Slc6a5,SLC6A5 solute carrier family 6 neurotransmitter transporter, glycine member 5,Slc6a9,Sodium and chloride dependent glycine transporter 2,Sodium- and chloride-dependent glycine transporter 2,Solute carrier family 6 member 5,Solute carrier family 6 neurotransmitter transporter glycine member 5

Background: This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia, a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 60kDa

Calculated_MW: 87kDa

Gene ID: 9152

UniProt: Q9Y345