BRWD1 antibody

Catalog No. ABIN6567606

This Rabbit Polyclonal antibody specifically detects BRWD1 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for BRWD1 antibody (ABIN6567606)

Target: BRWD1 (Bromodomain and WD Repeat Domain Containing 1 (BRWD1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRWD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BRWD1 Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human BRWD1 (NP_001007247.1).

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BRWD1

Target: BRWD1 (Bromodomain and WD Repeat Domain Containing 1 (BRWD1))

Alternative Name: BRWD1

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

Molecular Weight:

Observed_MW: 284kDa

Calculated_MW: 13kDa/248kDa/257kDa/262kDa

Gene ID: 54014

UniProt: Q9NSI6