Ataxin 3 antibody

Catalog No. ABIN6567724

This anti-Ataxin 3 antibody is a Rabbit Polyclonal antibody detecting Ataxin 3 in WB and IF. Suitable for Human and Mouse.

Quick Overview for Ataxin 3 antibody (ABIN6567724)

Target: Ataxin 3 (ATXN3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Ataxin 3 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ATXN3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Ataxin 3

Target: Ataxin 3 (ATXN3)

Alternative Name: ATXN3

Background:

Synonyms: AT3,Ataxin 3,ataxin 3 variant h,ataxin 3 variant m,ataxin 3 variant ref,Ataxin-3,ATX3,ATX3,ATXN3,EC 3.4.22.,JOS,Josephin,Machado Joseph disease (spinocerebellar ataxia 3,olivopontocerebellar ataxia 3,autosomal dominant,ataxin 3),Machado Joseph disease,Machado Joseph disease protein 1,Machado-Joseph disease protein 1,Machado-Joseph disease protein 1 homolog,MJD,MJD gene,MJD1,Olivopontocerebellar ataxia 3,OTTHUMP00000221583,OTTHUMP00000221585,OTTHUMP00000221586,OTTHUMP00000221587,OTTHUMP00000231995,OTTHUMP00000231997,Rsca3,SCA3,SCA3 gene,Spinocerebellar ataxia type 3 protein

Background: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight:

Observed_MW: 50kDa

Calculated_MW: 20kDa/35kDa/39kDa/41kDa

Gene ID: 4287

UniProt: P54252